Our goal is to help address an unmet need for people with sight-threatening retinal diseases, including Retinitis Pigmentosa (RP) and Geographic Atrophy in Dry AMD.
Read below for more information about these conditions.
Retinitis pigmentosa (RP)
Retinitis pigmentosa (RP) is an inherited eye condition where light-sensing cells (photoreceptor cells) in the retina gradually stop working. This results in worsening vision over a period of years or even decades, and ultimately leads to blindness. Some patients become blind as early as age 30; most patients become legally blind by their 40s or 50s.
RP is a major cause of inherited blindness, affecting about 1.5 million people throughout the world.
Geographic atrophy in dry-AMD
Geographic atrophy (GA) in dry age-related macular degeneration (dry-AMD) is an eye disorder where the cells of the macula (the middle part of the retina at the back of the eye) gradually stop working. It often develops over many years, as the cells die off and are not renewed, and can affect one or both of the eyes. It does not cause total blindness, but it can make everyday activities like reading and recognising faces difficult.
GA in dry-AMD typically occurs in people over 50 but can happen earlier. Approximately 5 million globally have GA in at least one eye. In the UK, GA is estimated to cause 26% of cases of legal blindness.